First listed on: 26 September 2018

CSIRO Postdoctoral Fellowship in Theranostic and Diagnostic Development

  • Do you have a strong background in molecular biology/genomics?
  • Develop novel therapeutics and diagnostics to treat cancers with low survival rates
  • Work as part of a dynamic multi-disciplinary team in this exciting postdoctoral fellowship

The Position:

Postdoctoral Fellows are appointed for up to three years and will work closely with a leading Research Scientist or Engineer in their respective field. They carry out innovative, impactful research of strategic importance to CSIRO with the possibility of novel and important scientific outcomes. They present the findings in appropriate publications and at conferences.

The Postdoctoral Fellow will undertake both bioinformatics and molecular biology work as part of a dynamic multi-disciplinary team developing novel therapeutics and diagnostics to treat cancers with low survival rates. The research will utilise large genomics databases to identify 1) targets for the development of next generation nanotechnologies and 2) companion diagnostics for precision oncology. After target identification, the fellow will develop liquid biopsy diagnostic assays using modern clinical platforms such as NGS and droplet digital PCR.

A strong background in molecular biology/genomics is essential, as well as capability in bioinformatics, particularly in the use of R/Bioconductor and Python. The fellow will have formal support to expand their bioinformatics skillset as part of the CSIRO postdoctoral development program.

The Diagnostics Team in North Ryde, NSW has a long history in oncology biomarker development, including the co-development of Colvera(tm) with the Clinical Genomics company. Colvera(tm) is a biomarker product for diagnosing and monitoring the recurrence of colorectal cancer and the development team was awarded a Eureka prize for Innovation in Medical Research last year.

Your duties will include:

  • Under the direction of senior research scientists, carrying out innovative, impactful research of strategic importance to CSIRO that will, where possible, lead to novel and important scientific outcomes.
  • Developing innovative concepts, theories, tools and techniques related to the analysis and integration of transcriptomic and epigenomic data.
  • Developing DNA methylation assays and test these on clinical samples.
  • Undertaking regular reviews of relevant literature and patents.
  • Producing high quality scientific and/or engineering papers suitable for publication in quality journals, for client reports and granting of patents.

Location:  Sydney, NSW
Salary: $82k to $93k plus up to 15.4% superannuation
Tenure: Specified term of up to 3 years
Job ref: 58754

To be successful you will have:

  • A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area, such as molecular biology, (epi)genetics or bioinformaticsPlease note: To be eligible for this role you must have no more than 3 years of relevant postdoctoral experience.
  • High level written and oral communication skills with the ability to represent the research team effectively internally and externally, including at national and international conferences.
  • Demonstrated knowledge and understanding of molecular biology, including lab experience.
  • Experience in bioinformatics for the analysis and interpretation of genomics datasets.
  • Familiarity with epigenetics principles.
  • Demonstrated proficiency in data analysis using R, Python/Numpy or MATLAB.

Before applying please view the full position details and selection criteria here: Position Details

About Us

We imagine. We collaborate. We innovate. At CSIRO, we do the extraordinary every day. We innovate for tomorrow and help improve today – for our customers, all Australians and the world. We do this by using science and technology to solve real issues. Diversity is the compass that navigates our innovation. We provide an inclusive workplace that respects, values and actively pursues the benefits of a diverse workforce.

We work flexibly at CSIRO, offering a range of options for how, when and where you work. Talk to us about how this role could be flexible for you. Find out more Balance

How to Apply: Please provide enough information relevant to the selection criteria for this position to enable the assessment panel to determine your suitability, and upload one document containing your CV/resume and cover letter.  

Applications Close: 10:59pm AEDT, 31 October 2018.

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